Deno is different and far better than using Node. Deno is an up-gradation of Node runtime developed by the same person to overcome some Node disadvantages. Instead of changing the Node version, Deno, a separate framework, is created as the Node is being widely used. But Deno has many advantages over Node like- cross-platform compatibility, Typescript support, more secure, rich-standard library, browser-event compatibility, etc.
If you have prior knowledge of the Node or an experienced Node developer, you might find it easy to learn Deno. Deno is just an upgrade to some Node concepts but works exactly the same as the Node. It will be a great learning Deno for future requirements in the market.
As per the market, the Node is still in use and widely accepted, making it a little difficult to move already running applications to Deno. But if we talk about the future and Deno's advantages, it may become the next popular runtime taking all the features into consideration.